Increases the solubility of calcium through urine

Phosphate is excreted in 90% of the kidneys and 10% of the feces

Inhibits the concentration between the tubule cell and the luminal fluid.

PHOSPHATE SANDOZ

In the distal renal tubule, the hydrogen secreted in the tubule cell is converted to sodium monobasic phosphate salts by substitution with sodium. Thus, a large amount of acid is secreted without lowering the pH of the urine to such an extent that it inhibits the transfer of hydrogen by a high concentration gradient between the tubule cell and the luminal fluid. This medicine increases the solubility of calcium in the urine.
It is absorbed through the gastrointestinal tract. However, high amounts of calcium or aluminum may cause insoluble phosphate and thus reduce its absorption. Phosphate is excreted in 90% of the kidneys and 10% of the feces.

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