
In the distal renal tubule, the hydrogen secreted in the tubule cell is converted to sodium monobasic phosphate salts by substitution with sodium. Thus, a large amount of acid is secreted without lowering the pH of the urine to such an extent that it inhibits the transfer of hydrogen by a high concentration gradient between the tubule cell and the luminal fluid. This medicine increases the solubility of calcium in the urine.
It is absorbed through the gastrointestinal tract. However, high amounts of calcium or aluminum may cause insoluble phosphate and thus reduce its absorption. Phosphate is excreted in 90% of the kidneys and 10% of the feces.
It is absorbed through the gastrointestinal tract. However, high amounts of calcium or aluminum may cause insoluble phosphate and thus reduce its absorption. Phosphate is excreted in 90% of the kidneys and 10% of the feces.
Fluid retention, high blood potassium, high blood sodium, high blood phosphate or calcium have been reported with this drug.
Sandoz phosphate is used to compensate for blood phosphorus deficiency. Acidification of urine due to this medicine increases the effect of medicines that require an acidic environment (such as methamphetamine) to exert their antibacterial effect. This medicine reduces the concentration of calcium in the urine and prevents the deposition of calcium in the urinary tract.
Contraindications to phosphate:
This medicine should not be used in patients with high blood phosphate, severe renal impairment and urinary stones, phosphate, magnesium-ammonium.
Concomitant use of calcium supplements with phosphates may increase the risk of calcium deposition in soft tissues. Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), captopril, cyclosporine, potassium-sparing diuretics, enalapril, heparin, and other potassium-containing drugs with potassium phosphate may increase blood potassium.
It can be used in special conditions and under the special supervision of a doctor: Animal studies have shown some side effects for the fetus and human studies are not sufficient. The benefits of the medicine against the potential risks determine whether or not to take the medicine during pregnancy.
Other Products